Ụlọ ọrụ ịma mma na-eme ike ya niile iji meju agụụ ụmụ nwanyị ka ọ bụrụ okenye.N'ime afọ ndị na-adịbeghị anya, a na-ejikarị peptides na-ekpo ọkụ na-arụ ọrụ na ụlọ ọrụ ịchọ mma.Ka ọ dị ugbu a, ndị na-emepụta ihe ịchọ mma a ma ama na mba ofesi ewepụtala ihe fọrọ nke nta ka ọ bụrụ ụdị akụrụngwa 50.N'ihi mgbagwoju anya nke ihe kpatara ịka nká, ụdị peptides dị iche iche mara mma na-arụ ọrụ pụrụ iche na usoro dị iche iche iji nweta nzube nke mgbochi wrinkle.Taa, ka anyị leba anya na peptides dị iche iche na ọnụọgụ dị na ndepụta ihe.
Nkewa ọdịnala ahụ kewara peptides mara mma site na usoro n'ime peptides Signal, Neurotransmitter na-egbochi peptides, na peptides ebu.
Otu.peptides mgbaàmà
peptides na-egosi na-akwalite njikọ nke protein matrix, karịsịa collagen, ma nwee ike ịbawanye mmepụta nke elastin, hyaluronic acid, glycosaminoglycans, na fibronectin.Ndị peptides ndị a na-akwalite njikọ nke collagen site n'ịbawanye ọrụ cell stromal, na-eme ka akpụkpọ ahụ dịkwuo mma ma na-eto eto.Yiri ihe ndị e ji alụ ọgụ ọgụ, dị ka vitamin C, vitamin A.Nnyocha nke P&G egosila na palmitoyl pentapeptide-3 na-akwalite mmepụta nke collagen na protein ndị ọzọ na-emepụta matrix extracellular, gụnyere elastin na fibronectin.Palmitoyl oligopeptides (palmitoyl tripeptide-1) na-eme otu ihe ahụ, nke mere palmitoyl oligopeptides na-ejikarị eme ihe.Palmitoyl pentapeptide-3, palmitoyl tripeptide-1, palmitoyl hexapeptide, palmitoyl tripeptide-5, hexapeptide-9 na nutmeg pentapeptide-11, nke a na-erekarị n'ahịa, bụ peptides mgbaàmà.
Abụọ.Neurotransmitter peptides
Nke a peptide bụ usoro dị ka botoxin.Ọ na-egbochi njikọ nnabata SNARE, na-egbochi mwepụta nke anụ ahụ nke acetycholine, na-egbochi ozi mkpirisi akwara na-ebufe akwara, ma na-eme ka akwara ihu dị jụụ iji mee ka ahụ dị mma.A na-eji peptides ndị a eme ihe n'ọtụtụ ebe dị ka peptides mgbaàmà ma dị mma maka ojiji na mpaghara ebe akwara okwu na-etinye uche (nkuku anya, ihu, na ọkpọiso).Ngwaahịa peptide na-anọchite anya ya bụ: acetyl hexapeptide-3, acetyl octapeptide-1, pentapeptide-3, dipeptide ophiotoxin na pentapeptide-3, n'ime nke a na-ejikarị bụ acetyl hexapeptide-3.
Atọ.Na-ebu peptides
Trieptides (Gly-L-His-L-Lys (GHK)) na plasma mmadụ nwere njikọ siri ike na ion ọla kọpa, nke nwere ike ịmepụta peptide ọla kọpa dị mgbagwoju anya (GHK-Cu).Mwepụ ọla kọpa bụ ihe dị mkpa maka ọgwụgwọ ọnya na ọtụtụ usoro mmeghachi omume enzymatic.Nnyocha egosiwo na GHK-Cu nwere ike ịkwalite uto, nkewa na ọdịiche nke mkpụrụ ndụ akwara na mkpụrụ ndụ ndị na-alụso ọrịa ọgụ, ma nwee ike ịkwalite ọgwụgwọ ọnya na germinal n'ụzọ dị irè.Ngwaahịa nke peptide ọla kọpa nọchiri anya ya bụ peptide ọla kọpa.
Anọ.ụdị peptides ndị ọzọ
Ọrụ n'ozuzu nke peptides ọdịnala bụ mgbochi wrinkle na mgbochi ịka nká ma e wezụga peptide ọla kọpa (peptide ọla kọpa nwere ọtụtụ ihe n'otu oge).N'ime afọ ndị na-adịbeghị anya, ụdị peptides dị iche iche na-amụbawanye, ụfọdụ n'ime ha na-enweta nzube nke mgbochi wrinkle na mgbochi ịka nká site na usoro ọhụrụ na echiche (mgbochi radical oxidation, mgbochi carbonylation, mgbochi mkpali, mgbochi mkpali, mgbochi. -edema na ịkwalite nrụzi dermal).
1. Mgbochi akpụkpọ anụ, na-akwalite ike akpụkpọ ahụ
Palmitoyl dipeptide-5, hexapeptide-8, ma ọ bụ hexapeptide-10 na-eme ka akpụkpọ ahụ sie ike site na ịkpali LamininV ụdị IV na VII collagen, ebe palmitoyl tetrapeptide-7 na-ebelata mmepụta interleukin-6 ma na-ebelata mbufụt.Ụdị peptide a na-arụ ọrụ na-arụ ọrụ nke ọma, ụdị ọhụrụ na-abawanye ụba mgbe niile, nke a na-ejikarị bụ palm tetrapeptide-7.
2. Glycosylation
Ndị peptides ndị a nwere ike ichebe collagen pụọ na mbibi na ịkekọrịta site na ụdị carbonyl reactive (RCS), ebe ụfọdụ peptides na-egbochi carbonyl nwere ike ịbọ ọbọ free radicals.Nlekọta akpụkpọ anụ ọdịnala na-etinye nnukwu mkpa na radicals n'efu, na-apụtawanye ìhè mgbochi carbonylation.Carnosine, tripeptide-1 na dipeptide-4 bụ peptides nwere ọrụ ndị dị otú ahụ
3. Meziwanye edema anya, meziwanye microcirculation ma mee ka mgbasa ọbara sie ike
Acetyltetrapeptide-5 na dipeptide-2 bụ ndị na-egbochi ACE nwere ike na-eme ka mgbasa ọbara dịkwuo mma site na igbochi ntụgharị nke angiotensin I na angiotensin II.
4. Kwalite mmezi dermal
Palmitoyl hexapeptidde-6, mkpụrụ ndụ peptide na-alụso ọrịa ọgụ, nwere ike kpalite mmụba na njikọ fibroblast nke ọma, njikọ collagen na mbugharị cell.
Peptides mgbochi ịka nká agụnyere ọtụtụ n'ime ha.Na mgbakwunye na peptides na-egbochi ịka nká nke a kpọtụrụ aha n'elu, a na-emepụta ọtụtụ peptides ịchọ mma ndị ọzọ na ụlọ ọrụ ahụ, dị ka ịcha ọcha, nkwalite ara, nkwụsị arọ na ihe ndị ọzọ.
Oge nzipu: Mar-22-2023