Ọdịiche dị na gburugburu ebe TFA salts, acetate, na hydrochloride na-eji peptide synthesis.

N'oge njikọ peptide, ọ dị mkpa ịgbakwunye nnu.Ma e nwere ọtụtụ ụdị nnu, na ụdị nnu dị iche iche na-eme ka peptides dị iche iche, mmetụta ya abụghịkwa otu.Yabụ taa, anyị na-ahọrọkarị ụdị nnu peptide kwesịrị ekwesị na njikọ peptide.

1. Trifluoroacetate (TFA): Nke a bụ nnu a na-ejikarị na ngwaahịa peptide, ma ọ dị mkpa ka a zere ya na ụfọdụ nnwale n'ihi biotoxicity nke trifluoroacetate.Dịka ọmụmaatụ, nnwale cell.

2. Acetate (AC): The biotoxicity nke acetic acid bụ nnọọ ihe na-erughị trifluoroacetic acid, ya mere, ọtụtụ pharmaceutical na ịchọ mma peptides na-eji acetate, ma ụfọdụ ngwaahịa nwere ejighị n'aka acetate, n'ihi ya, nkwụsi ike nke usoro dịkwa mkpa ka a tụlee.A họọrọ acetate maka ọtụtụ nnwale cell.

3. Hydrochloric acid (HCL): A naghị ahọrọ nnu a, naanị usoro ụfọdụ na-eji hydrochloric acid maka ebumnuche pụrụ iche.

4. Ammonium nnu (NH4 +): Nnu a ga-emetụta nke ukwuu na solubility na nkwụsi ike nke ngwaahịa ahụ, a ghaghị ịhọrọ ya.

5. Sodium nnu (NA +): ọ na-emetụta nkwụsi ike na solubility nke ngwaahịa.

6. Pamoicacid: A na-ejikarị nnu a eme ihe na ọgwụ peptide na-emepụta ihe na-adịgide adịgide.

7. CitricAcid: Nnu a nwere obere nsí physiological , ma nkwadebe ya dị nnọọ mgbagwoju anya, ya mere ekwesịrị ịmepụta usoro mmepụta ya n'usoro na iche iche.

8. Salicylicacid: Salicylate nwere ike imetụta nkwụsi ike nke ngwaahịa peptide, ya mere a na-ejikarị ya eme ihe.

Ihe dị n'elu bụ ụdị salts peptide dị iche iche, anyị kwesịkwara ịhọrọ dịka njirimara nke nnu dị iche iche na-eji eme ihe n'ezie.


Oge nzipu: Jun-16-2023