Nkọwa
Palmitoyl-Lysyl-Valyl-Lysine (Pal-Lys-Val-Lys-OH), nke a makwaara dị ka “tripeptide” ma ọ bụ “collagen peptide Col-O2”, bụ peptide mbụ na nke a na-ejikarị eme ihe.Palmitoyl tripeptide-8 bụ peptide na-egosi na-akwalite njikọ nke Chemicalbook na extracellular matrix protein mmepụta nke collagen (ụdị).Ⅰ, ⅡnaⅣ) site n'ịbawanye ọrụ cell stromal, na-eme ka akpụkpọ ahụ yie ka ọ dị obere na nke siri ike karị.Mgbe agbakwunyere ihe ịchọ mma, ọ nwere ike inye aka mejupụta collagen na akpụkpọ ahụ, meziwanye ngbanwe ihu ma belata nhụsianya ihu nke ukwuu.N'otu oge ahụ, ọ nwekwara njirimara nke ịkwalite ọrụ cell, ịba ụba nke mmiri anụ ahụ, ime ka akpụkpọ ahụ dịkwuo mma na ime ka ụda akpụkpọ ahụ dịkwuo mma.Mee ka ọ dị n'ime anụ ahụ na njigide mmiri, mee ka akpụkpọ ahụ dị nro ma dị nro, site n'ime ime ka akpụkpọ ahụ dịkwuo mma.
Nkọwapụta
Apperance: White na-acha ọcha ntụ ntụ
Ịdị ọcha (HPLC):≥98.0%
Otu adịghị ọcha:≤2.0%
Ọdịnaya Acetate (HPLC): 5.0%~12.0%
Ọdịnaya Mmiri (Karl Fischer):≤10.0%
Ọdịnaya Peptide:≥80.0%
Mbupu na mbupu: Okpomọkụ dị ala, nkwakọ ngwaahịa agụụ, ziri ezi na mg dị ka achọrọ.
Kedu ka esi ịtụ ahịa?
1. Contact us directly by phone or email: +86-13735575465, sales1@gotopbio.com.
2. Nye iwu online.Biko dejupụta akwụkwọ a chọrọ n'ịntanetị.
3. Nye aha peptide, CAS No. ma ọ bụ usoro, ịdị ọcha na mgbanwe ma ọ bụrụ na achọrọ, ọnụ ọgụgụ, wdg anyị ga-enye nkwupụta n'ime awa 2.
4. Nye iwu nkwekọrịta site n'aka nkwekọrịta ire ahịa nke ọma na NDA(nkwekọrịta enweghị nkwupụta) ma ọ bụ nkwekọrịta nzuzo.
5. Anyị ga-anọgide na-emelite ọganihu usoro n'oge.
6. A ga-enyefe Peptide site na DHL, Fedex ma ọ bụ ndị ọzọ, na HPLC, MS, COA na ibu.
7. A ga-agbaso iwu nkwụghachi ma ọ bụrụ na enwere ọdịiche nke àgwà ma ọ bụ ọrụ anyị.
8. Mgbe-sale ọrụ: Ọ bụrụ na anyị ahịa nwere ajụjụ ọ bụla banyere anyị peptide n'oge nnwale, biko na-eche free ịkpọtụrụ anyị na anyị ga-aza ya na a obere oge.
A na-eji ngwaahịa niile nke ụlọ ọrụ ahụ naanị maka ebumnuche nyocha sayensị, ya'Amachibidoro ka onye ọ bụla jiri ya mee ihe n'ahụ mmadụ.
FAQ
Kedu ihe mgbochi na ogologo peptides sịntetik?
The polypeptide synthesized anyị ụlọ ọrụ bụ 6 ~ 50 amino asịd n'ogologo.Usoro nhazi usoro siri ike na-emepụtakarị peptides nke amino acid 6 ruo 50.
Otu esi akọwa ọnụ ọgụgụ P+Na na P+K na MALDI(MS)?
A na-ahụkarị ọnụ ọnụ Na na K na MALDI, sodium na potassium na-esite na mmiri mgbaze.Ọbụna mmiri a kpụkọrọ akpụkọ na deionized nwere ike ịnwe ion sodium na potassium nke enweghị ike iwepụ kpamkpam.Ha na-etinyekwa ionize ma jikọta na otu carboxyl efu nke peptide n'oge spectrometry mass.N'ihi na enweghị usoro nchacha iji wepụ sodium na potassium ion na mmiri, ọ bụ ihe a na-apụghị izere ezere mgbe ụfọdụ na ọnụ ọgụgụ sodium na potassium na-apụta na map MALDI MS.
Biko kọwaa atụmatụ ịsacha ọcha gị
A na-asachapụ peptides nke ụlọ ọrụ anyị rụpụtara site na nkwadebe ntụgharị-phase HPLC na TFA na pH 2 agbakwunyere na usoro mkpanaka abụọ ahụ.Usoro A bụ 0.1% TFA na mmiri ultra-dị ọcha, na akụkụ B bụ 0.1% TFA na ACN, pH 2. Enwere ike ịgbaze ihe nlele ahụ ozugbo na oge A, ma ọ bụ gbazee na obere ego nke B ma tinye ya na A nkeji.Mgbe ụfọdụ, ọ nwere ike ịdị mkpa igbari hydrophobic peptides na ihe mgbaze siri ike dị ka formic acid ma ọ bụ acetic acid, dabere na usoro nke peptide.Na pH 6.8, ọ na-esiri ike igbari na sachaa peptide ahụ, yabụ anyị na-agbari peptide mbụ wee jiri usoro mkpanaka abụọ maka gradient elution.Ngwọta nchekwa na pH 6.8 bụ 10 mM ammonium acetate na mmiri ultra-dị ọcha (usoro mkpanaka A), ACN dị ọcha (usoro mkpanaka B).MADLI-TOF MS chịkọtara ma chọpụta akụrụngwa dị iche iche.Atụlela ịdị ọcha site na mgbagha HPLC.Mgbe ahụ, a na-eme ka peptides lekwasịrị anya lyophilized, na-ejikọta peptides lyophilized n'ime obere vial.
Kedu otu esi enyocha ngwaahịa gị?
HPLC na MS nyochara peptides niile sịntetik, ewezuga MALDIMS.Ebe ọ bụ na peptides bụ ionized n'usoro nke ha na spectrometers dị iche iche, HPLC-MS usoro nwere ike iji nyochaa ọnụ ọgụgụ kasị elu nke ionization na HPLC.Ngwá ọrụ teknụzụ anyị [MALDI-MS, HPLC- (ESI) MS (ion trap na tetrode array)] na-enye mmesi obi ike maka nyocha.
Solubility nke peptide nwere njikọ na ogo nke peptide?
Ihe peptides sịntetik anaghị agbaze nke ọma, peptides nwere nsogbu, nri?
A: O siri ike ịkọ kpọmkwem otú peptide siri ike na ihe mgbaze kwesịrị ekwesị bụ.Ọ bụghị eziokwu na enwere nsogbu na peptide synthesis ma ọ bụrụ na ọ siri ike igbari.
Kedu ka esi echekwa peptides na ngwọta?
Ọ bụrụ na ị ga-echekwarịrị peptides gị n'ime mmiri mmiri, jiri ihe nchekwa igba ogwu na PH 5-6 wee chekwaa na -20.℃ịgbatị ndụ nke peptides gị na ngwọta.
Ogologo oge ole ka peptides na-adịru na ngwọta?
Ọ kacha mma ka ị ghara ịchekwa peptides fọdụrụnụ na ngwọta.Ndụ nchekwa nke polypeptides na ngwọta dị oke oke, ọkachasị ndị nwere cysteine, methionine, tryptophan, asparagic acid, glutamic acid na N-terminal glutamic acid n'usoro.N'ozuzu, wepụ mkpa ego nke ojiji, ndị fọdụrụ n'ime ifriizi Fikiere maka ogologo oge nchekwa.