A na-ejikarị Palmitoyl pentapeptide-4 mee ihe dị ka ihe mgbakwasị ụkwụ maka ngwaahịa nlekọta anụ ahụ na-eme ka akpụkpọ ahụ kwụsị.
Palmitoyl pentapeptide-4 (tupu 2006 palmitoyl pentapeptide-3) ka a na-ejikarị dị ka jel ntọala maka ngwaahịa nlekọta anụ ahụ na-agbake nhịahụ.Ọ bụ site n'aka ndị na-ahụ maka nlekọta anụ ahụ na-emepụta ihe na-emepụta ihe na-emepụta ihe na 2000 dị ka ụlọ ọrụ nlekọta onwe ha dị ka ihe na-arụ ọrụ, palmitoyl pentapeptide-4 bụ usoro peptide nke a na-ejikarị eme ihe na nke a na-ejikarị polypeptide eme ihe, ụdị ụlọ na ndị mba ọzọ a ma ama na-ejikarị eme ihe dị ka ihe eji eme ihe. ihe bụ isi dị irè mgwa na mgbochi-a wrinkle firming anụ na-elekọta, na ọtụtụ mgbochi wrinkle firming akpụkpọ nlekọta ngwaahịa na-apụtakarị na ọnụ ọgụgụ ya.Site na ịba ụba collagen site na dermis, ọ nwere ike gbanwee usoro ịka nká site n'ịrụghachi akpụkpọ ahụ site n'ime.Na-emetụta collagen, eriri na-agbanwe na hyaluronic acid na-abawanye, na-abawanye ọdịnaya mmiri anụ ahụ na njigide mmiri, na-abawanye ọkpụkpụ akpụkpọ ahụ ma belata ahịrị dị mma.
Palmitoyl pentapeptide-4 (Pal-lys-thr-Lys-ser = Pal-KTTKS) nwere amino asịd ise jikọtara na 16-carbon aliphatic chains iji kwalite permeability nke molekul site na lipid nhazi nke akpụkpọ ahụ.Nke a bụ margarine.Palmitoyl pentapeptide-4 bụ peptide ozi na-achịkwa ike ndụ cell site na iso ndị nabata ha na-emekọrịta ihe.Ha kpalitere mkpụrụ ndụ ihe nketa na-etinye aka na nkwalite nke matriks extracellular na mmụba cell.Palmitoyl pentapeptide-4 nwere mmetụta mgbochi mgbochi na mgbochi akpụkpọ site na ịgbalite njikọ ọhụrụ nke macromolecules na matrix extracellular.
Usoro ihe omume
Nnyocha ọmụmụ vitro chọpụtara mmụba 212% na ụdị collagen nke m, mmụba 100% ruo 327% na ụdị IV collagen synthesis, yana mmụba 267% na njikọ hyaluronic acid.A na-ahụ Collagen I n'ụdị dị iche iche nke 19 nke collagen n'ime ahụ.Ya mere, ịba ụba mkpokọta mmepụta nke collagen I nwere mmetụta dị ukwuu na iwughachi akpụkpọ ahụ.The ọnwa isii na vivo ọmụmụ chọpụtara na nkezi mbelata nke 17 pasent na omimi nke ezi ahịrị, 68 percent na elu ebe nke miri ezi ahịrị, 51 percent na elu ebe nke agafeghị oke ezi ahịrị, na 16 pasent na roughness nke. akpụkpọ anụ.
Oge nzipu: Eprel-28-2023